Cancer Immunotherapy: Priming the Host Immune Response with Live Attenuated Salmonella enterica
نویسندگان
چکیده
منابع مشابه
Immune responses to recombinant pneumococcal PspA antigen delivered by live attenuated Salmonella enterica serovar typhimurium vaccine.
Attenuated Salmonella enterica serovar Typhimurium expressing recombinant antigens from other pathogens elicits primarily a Th1-type dominant immune response to both recombinant and Salmonella antigens. The immunogenicity and appropriate subcellular location of the recombinant antigen in the Salmonella vaccine strain may contribute to augmenting immune responses by facilitating adequate exposur...
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Studies of mouse models of endotoxemia and sepsis with gram-negative bacteria have shown that the host response is genetically controlled. Mice infected with the gram-negative bacterium Salmonella enterica serovar Typhimurium exhibit marked genetic differences in disease manifestation, and the wild-derived strain Mus musculus molossinus MOLF/Ei is extremely susceptible to S. enterica serovar Ty...
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African swine fever (ASF) is a lethal hemorrhagic disease of swine caused by a double-stranded DNA virus, ASF virus (ASFV). There is no vaccine to prevent the disease and current control measures are limited to culling and restricting animal movement. Swine infected with attenuated strains are protected against challenge with a homologous virulent virus, but there is limited knowledge of the ho...
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Foodborne infections caused by Salmonella enterica serovars are a significant problem worldwide. Presented here is the genome sequence of the nontyphoidal S. enterica serovar Typhimurium mutant strain NC983, a potential vaccine candidate.
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Evaluation of protective efficacy of live attenuated Salmonella enterica serovar 1 Gallinarum vaccine strains against fowl typhoid in chickens 2 3 Paweł Łaniewski, Arindam Mitra, Kemal Karaca, Ayub Khan, Rajeev Prasad, 4 Roy Curtiss III, Kenneth Roland 5 6 The Biodesign Institute and School of Life Sciences, Arizona State University, 7 Tempe, AZ, USA 8 Global Biological Research and Development...
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ژورنال
عنوان ژورنال: Journal of Immunology Research
سال: 2018
ISSN: 2314-8861,2314-7156
DOI: 10.1155/2018/2984247